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The Best Supplements for Muscle Gain and Strength

Updated: Jan 26

Building muscle and increasing strength can feel overwhelming at first, especially when it comes to choosing the right supplements. With countless options on the market, beginners often wonder which supplements actually work and are safe to use. This post breaks down five beginner-friendly supplements that have solid research backing their effectiveness for muscle gain and strength. You’ll learn about their benefits, recommended dosages, and potential side effects to help you make informed decisions on your fitness journey.



Eye-level view of a clear shaker bottle filled with protein shake on a gym bench
A shaker bottle with protein shake on gym bench


1. Whey Protein


Whey protein is one of the most popular and well-researched supplements for muscle growth. It is a complete protein containing all nine essential amino acids, which are crucial for muscle repair and growth.


Benefits

  • Supports muscle protein synthesis: Whey protein provides a quick source of amino acids, especially leucine, which triggers muscle building.

  • Promotes recovery: Consuming whey after workouts helps reduce muscle soreness and speeds up recovery.

  • Convenient and fast-absorbing: It digests quickly, making it ideal post-workout.


Recommended Dosage

  • Aim for 20-30 grams of whey protein within 30 minutes after training.

  • Total daily protein intake should be around 1.6 to 2.2 grams per kilogram of body weight, with whey supplementing dietary protein.


Research Findings

A 2018 meta-analysis published in the British Journal of Sports Medicine found that whey protein supplementation combined with resistance training increased muscle mass by an average of 1.3 kg more than training alone over several weeks.


Potential Side Effects

  • Generally safe for most people.

  • Those with lactose intolerance may experience digestive discomfort.

  • Choose high-quality whey isolate if lactose sensitivity is an issue.



2. Creatine Monohydrate


Creatine is one of the most studied supplements for strength and muscle gain. It naturally occurs in muscles and helps regenerate ATP, the primary energy source during high-intensity exercise.


Benefits

  • Increases strength and power: Creatine supplementation can improve performance in short bursts of intense activity.

  • Supports muscle growth: It promotes cell volumization, which may stimulate muscle protein synthesis.

  • Enhances recovery: Creatine can reduce muscle damage and inflammation after workouts.


Recommended Dosage

  • Start with a loading phase of 20 grams per day split into 4 doses for 5-7 days (optional).

  • Then maintain with 3-5 grams daily.

  • Consistent daily intake is key for best results.


Research Findings

A study in the Journal of Strength and Conditioning Research showed that creatine users gained 1.4 to 2.2 kg more lean muscle mass over 4 weeks compared to placebo.


Potential Side Effects

  • Safe for healthy individuals when taken as recommended.

  • Some may experience water retention or mild stomach upset.

  • Stay hydrated to avoid cramps.



3. Branched-Chain Amino Acids (BCAAs)


BCAAs include leucine, isoleucine, and valine, essential amino acids that play a role in muscle metabolism.


Benefits

  • Reduces muscle soreness: BCAAs can decrease muscle damage and soreness after exercise.

  • Supports muscle protein synthesis: Leucine in particular activates pathways that build muscle.

  • May reduce exercise fatigue: Helps delay central fatigue during prolonged workouts.


Recommended Dosage

  • 5-10 grams before or during workouts.

  • Can be taken throughout the day if dietary protein is low.


Research Findings

A 2017 review in Nutrients reported that BCAA supplementation reduced muscle soreness by 20% and improved recovery markers in resistance-trained individuals.


Potential Side Effects

  • Generally well tolerated.

  • Excessive intake without adequate water may cause digestive issues.



4. Beta-Alanine


Beta-alanine is a non-essential amino acid that increases muscle carnosine levels, which buffers acid in muscles during intense exercise.


Benefits

  • Improves muscular endurance: Helps delay muscle fatigue during high-rep sets or intense cardio.

  • Enhances strength performance: Allows for more reps or longer training sessions.

  • Supports muscle growth indirectly: By enabling harder training.


Recommended Dosage

  • 2-5 grams daily.

  • Split doses to reduce tingling sensation (paresthesia) that some experience.


Research Findings

Research published in Amino Acids found that beta-alanine supplementation improved exercise capacity by 13% and increased training volume.


Potential Side Effects

  • Tingling or itching sensation on skin is common but harmless.

  • Can be minimized by dividing doses.



5. Fish Oil (Omega-3 Fatty Acids)


Fish oil supplements provide omega-3 fatty acids EPA and DHA, which have anti-inflammatory properties.


Benefits

  • Reduces muscle soreness and inflammation: Helps recovery after intense workouts.

  • Supports joint health: Important for maintaining mobility during training.

  • May improve muscle protein synthesis: Emerging research suggests omega-3s enhance anabolic response to protein.


Recommended Dosage

  • 1-3 grams of combined EPA and DHA daily.

  • Choose high-quality, purified fish oil supplements.


Research Findings

A study in the American Journal of Clinical Nutrition showed that older adults taking omega-3 supplements increased muscle protein synthesis by 30% compared to placebo.


Potential Side Effects

  • Generally safe.

  • High doses may increase bleeding risk; consult a doctor if on blood thinners.



Final Thoughts - Best Supplements for Muscle Gain and Strength


Starting your muscle gain and strength journey with the right supplements can make a noticeable difference. Whey protein and creatine monohydrate stand out as the most effective and beginner-friendly options, backed by strong scientific evidence. BCAAs, beta-alanine, and fish oil offer additional benefits that support recovery, endurance, and overall muscle health.


This article aims to spotlight the best supplements for muscle gain and strength. For more detailed and comprehensive posts on each supplement, please explore the other blogs available.




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